NCCTG
North Central Cancer Therapy Group (a research base).
NCI
National Cancer Institute.
Necrosis
Death of cells in an organ/tissue.
Neoplasia
New/abnormal growth of tissue, may form a tumor/mass, may be non-cancerous or cancerous.
Neuroblastoma
Type of cancer developing from early form of nerve cells.
Neutropenia
Decrease in common type of the white blood cells important to fight infections.
NIH
National Institute of Health.
NSABP
National Surgical Adjuvant Breast and Bowel Program (a “specialty” research base, now a part of NRG).
Occlusion
Closing; obstruction of a hollow organ, eg: blood vessel
OHRP
Office of Human Research Protection.
Oncology
A specialty which deals with prevention and treatment of cancer.
OPRR
Office of Protection from Research Risks of the NIH, oversees IRBs and related matters.
Optimal
Best/most favorable or desirable.
Oral Administration
Given by mouth.
Osteopetrosis
Rare inherited bone disorder characterized by hard bone(stone bone)
Osteoporosis
Bone disorder characterized by loss of bone leading to increased risk of fracture.
Parenteral
Administration by route other than mouth and alimentary canal.
Pathogenesis
Origination and development of disease.
Phase I
Testing a drug in healthy volunteers to determine limits of tolerance.
Phase II
Clinical trial / testing done on patients to assess patient safety and efficay.
Phase III
Usually a big randomized clinical trial to confirm and expand information on safety and usefulness of a new drug.
Phlebitis
Irritation or inflammation of a vein.
Placebo
An inactive substance which may resemble an active agent but has no medicinal value.
Placebo Effect
Symptom or change of condition seen when a placebo is given; not attributable to an active drug agent.
Platelets
A component of blood that helps in clotting of blood (stops bleeding).
Potentiator
An agent that helps another agent work better.
PRN
As and when needed.
Prognosis
Likely course of a disease/probable outcomes.
Prophylaxis
A drug given to prevent disease or infection.
Prospective Study
A study following patients forward in time.
Protocol
A document with a plan for a scientific experiment/medical treatment.
Proximal
Situated closer to the center of the body, away from the end.
Pulmonary
Pertaining to the lungs.
QD
Every day; daily.
QID
Four times a day.
Radiation Therapy
Type of cancer treatment using high energy waves to kill cancer ells/ X-ray or cobalt treatment.
Random
By chance.
Randomization
Assignment of treatment group by chance, similar to tossing a coin (when there is more than one treatment choice).
RBC
Red blood cell.
Recombinant
Resulting from new combinations of genes(genetic material).
Recur
Appears again /returns.
Refractory
Stubborn/resistant/ not responding to treatment.
Regeneration
Formation/restoration/regrowth of a structure or of lost tissue.
Regimen
Plan or prescribed course of medical treatment.
Relapse
Return or reappearance of a disease after initial improvement.
Remission
Decrease / disappearance of evidence of cancer or other disease.
Renal
Pertaining to the kidneys.
Resect
Remove or cut out tissue or a part of an organ surgically.
Retrospective Study
Historic study /study looking back over past experience.
RTOG
Radiation Therapy Oncology Group ( a research group, now a part of NRG).