Abdominal
Pertaining to body cavity below diaphragm which contains stomach, intestines, liver and other organs.
Acidosis
Increased acid in blood and other body tissue
Acuity
Acuteness, clearness, keenness, especially of vision or airways
Acute
New, recent, sudden onset
Adenopathy
Swollen lymph nodes (glands).
Adjuvant
A medication that modifies the effect of other agents/medications.
Adjuvant Treatment
Treatment given in addition to primary/initial treatment(surgery) to decrease the risk of cancer coming back.
ADR
Adverse Drug Reaction-harmful / unintended reaction resulting from administration of a medication.
Adverse Event (AE)
Unfavorable and Unintended side effect.
Allergic Reaction
Rash, Itchy eyes, running nose, trouble breathing, nausea, diarrhea.
Anaphylaxis
Rapid in onset, serious, potentially life threatening allergic reaction.
Anemia
Decreased red blood cells / low red blood cell count.
Anorexia
Condition in which a person cannot eat due to lack of appetite.
Antimicrobial
Drug that kills bacteria and other germs.
Assay
Investigative procedure like a lab test.
Benign
Not cancerous, usually without serious consequences, but with some exceptions ie. benign brain tumor may have serious consequences.
Binding/Bound
Carried by, to make stick together, transported.
Bioavailability
Dose of the administered drug or other substance available to target tissue in the body.
Blood profile
Series of blood tests.
Bolus
A discrete amount of drug / medication given at once to increase the concentration of the drug in blood to an effective level.
Bone Mass
The amount of calcium in a given amount of bone.
CALGB
Cancer and Leukemia Group B (a “specialty” Research Base for cancers – now under Alliance ).
Carcinogenic
Capable of causing cancer.
Carcinoma
Is a form of cancer that makes up the majority of cases of malignancy.
NCORP
National Cancer Institute Community Oncology Research Program.
Chemotherapy
Type of treatment for cancer.
Chronic
Continuing for a long time / Longstanding.
Cisplatin
A chemotherapy drug used to kill cancer cells.
Clinical Trial
An experiment done on human participants to answer specific questions about new treatments.
Clinically Significant
Major/practical importance of treatment effect.
Complete response (CR)
Total disappearance of all disease.
Consolidation Phase
More treatment to eliminate non detectable disease and prevent disease from coming back.
Controlled Trial
Study in which the experimental treatment or procedure is compared to a standard /control treatment or procedure.
Cooperative Group
Association of multiple institutions to perform clinical trials.
CRO
Cancer Research for the Ozarks.
CT (CAT) Scan
Computerized (axial) tomography; computerized series of x-rays to detect abnormalities in various internal organs, like chest, abdomen and pelvis.
Cumulative
Total sum (of individual events, experiences, treatments).